' 
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.7
USERS' SCORE
Good
Based on 13 Reviews
8.3
Supplement Facts
Serving Size: 1 Fish Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
<5 mg
1%
Vitamin D3 (as Cholecalciferol) (from Lanolin)
25 mcg (1,000 IU)
125%
Fish Oil Concentrate
1.2 g (1,200 mg)
†
Omega-3 Fatty Acids:
Eicosapentaenoic Acid (EPA)
600 mg
†
Docosahexaenoic Acid (DHA)
300 mg
†
Top Medical Research Studies
9
Omega-3 levels reduce heart failure
Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities.
Significant positive health implications
We investigated the link between plasma omega-3 levels and the risk of heart failure (HF) in a large UK cohort study. Our analysis revealed that higher omega-3 levels were associated with a 21% lower chance of developing HF over nearly 14 years.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
Read More
9
Omega-3 reduces cardiovascular risk
Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial.
Findings show clear clinical relevance.
We observed the effects of icosapent ethyl on heart health in a significant clinical trial involving statin-treated patients at high risk for cardiovascular events. This post hoc analysis revealed that icosapent ethyl reduced major cardiovascular issues, regardless of whether patients had low-density lipoprotein cholesterol (LDL-C) levels below or above 55 mg/dL.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
Read More
8
Eicosapentaenoic acid reduces arrhythmia
Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice.
Validates EPA's cardiovascular benefits
We explored the impact of eicosapentaenoic acid (EPA) on heart health by studying mice on a high-fat diet. Those supplemented with EPA showed a significant reduction in atrial fibrillation compared to those without. While 100% of the high-fat diet mice developed atrial fibrillation, only 50% of those receiving EPA did, and their episodes were shorter.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
Read More
Most Useful Reviews
7.5
Supports cardiovascular system
This omega with vitamin D in a single capsule is excellent! The quality is assured by the reputable brand Now Foods. The ingredients include fish oil (anchovy) and fish gelatin. I regularly give this omega to my parents, aged 67, at a daily dose of one capsule with meals. The cost-effective packaging provides 180 capsules, lasting a long time. I recommend it for supporting cardiovascular health.
Read More
9.5
Miraculous health benefits
This Omega-3 has an excellent EPA and DPA ratio, plus vitamin D. I've taken it consistently for a year and a half, only from NOW, and plan to continue. Remarkably, I haven’t suffered from a cold for that time, and my chronic sinusitis has disappeared, which is miraculous for me! Overall, it's made a significant difference in my health and I have no hesitation in recommending it.
Read More
9.5
Stable lipid profile
A must-have! I have been taking this consistently since March 2020. After a comprehensive health examination in February 2021, my lipid profile results were normal, and my cardiovascular system is healthy. The quality of the raw materials from Now Foods is impressive, especially with the added vitamin D. I have been pleased with all their products and exclusively purchase supplements from IHerb due to their reliability and quality.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.7
- All Researches
9
Omega-3 reduces cardiovascular risk
Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial.
Findings show clear clinical relevance.
We observed the effects of icosapent ethyl on heart health in a significant clinical trial involving statin-treated patients at high risk for cardiovascular events. This post hoc analysis revealed that icosapent ethyl reduced major cardiovascular issues, regardless of whether patients had low-density lipoprotein cholesterol (LDL-C) levels below or above 55 mg/dL.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
Read More
9
Omega-3 improves heart function
The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
High relevance and statistical significance
We assessed how omega-3 fatty acids (PUFAs) can support heart failure management through a thorough network meta-analysis of 14 studies with nearly 9,100 participants.
Our findings revealed that high doses (2,000-4,000 mg/day) taken for at least one year significantly improved heart function, particularly the left ventricular ejection fraction and peak oxygen consumption.
However, lower doses and shorter durations were not effective, and we found no major differences in safety measures like dropout rates or overall mortality between those taking omega-3 and those who were not.
Our findings revealed that high doses (2,000-4,000 mg/day) taken for at least one year significantly improved heart function, particularly the left ventricular ejection fraction and peak oxygen consumption.
However, lower doses and shorter durations were not effective, and we found no major differences in safety measures like dropout rates or overall mortality between those taking omega-3 and those who were not.
Read More
9
Omega-3 levels reduce heart failure
Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities.
Significant positive health implications
We investigated the link between plasma omega-3 levels and the risk of heart failure (HF) in a large UK cohort study. Our analysis revealed that higher omega-3 levels were associated with a 21% lower chance of developing HF over nearly 14 years.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
Read More
8
Omega-3s are safer for hearts
EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines.
Relevant for heart disease risk
This study examined how different fatty acids affect heart health, particularly focusing on long-chain acylcarnitines. We found that saturated and monounsaturated acylcarnitines, especially one type called trans-elaidoylcarnitine, can significantly harm heart function and cell viability.
On the other hand, omega-3 derived acylcarnitines like eicosapentaenoylcarnitine and docosahexaenoylcarnitine showed minimal negative effects. In fact, they did not impair heart function or cell viability, suggesting that omega-3 fish oil might be a safer option for people with heart issues compared to other fatty acid sources.
On the other hand, omega-3 derived acylcarnitines like eicosapentaenoylcarnitine and docosahexaenoylcarnitine showed minimal negative effects. In fact, they did not impair heart function or cell viability, suggesting that omega-3 fish oil might be a safer option for people with heart issues compared to other fatty acid sources.
Read More
8
Eicosapentaenoic acid reduces arrhythmia
Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice.
Validates EPA's cardiovascular benefits
We explored the impact of eicosapentaenoic acid (EPA) on heart health by studying mice on a high-fat diet. Those supplemented with EPA showed a significant reduction in atrial fibrillation compared to those without. While 100% of the high-fat diet mice developed atrial fibrillation, only 50% of those receiving EPA did, and their episodes were shorter.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
Read More
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Supports cardiovascular system
This omega with vitamin D in a single capsule is excellent! The quality is assured by the reputable brand Now Foods. The ingredients include fish oil (anchovy) and fish gelatin. I regularly give this omega to my parents, aged 67, at a daily dose of one capsule with meals. The cost-effective packaging provides 180 capsules, lasting a long time. I recommend it for supporting cardiovascular health.
Read More
9.5
Miraculous health benefits
This Omega-3 has an excellent EPA and DPA ratio, plus vitamin D. I've taken it consistently for a year and a half, only from NOW, and plan to continue. Remarkably, I haven’t suffered from a cold for that time, and my chronic sinusitis has disappeared, which is miraculous for me! Overall, it's made a significant difference in my health and I have no hesitation in recommending it.
Read More
9.5
Stable lipid profile
A must-have! I have been taking this consistently since March 2020. After a comprehensive health examination in February 2021, my lipid profile results were normal, and my cardiovascular system is healthy. The quality of the raw materials from Now Foods is impressive, especially with the added vitamin D. I have been pleased with all their products and exclusively purchase supplements from IHerb due to their reliability and quality.
Read More
7.5
Lowering cholesterol
This omega offers a good price-quality ratio, with an excellent balance of EPA and DHA, supporting the cardiovascular system and playing a vital role in maintaining health and lowering cholesterol levels.
7.8
Convenient nutrient source
The convenience of having 900 mg of EPA + DHA along with a recommended vitamin D dosage in one capsule is remarkable. This supplement addresses essential nutrients critical for health. I advocate for its usage on a global scale to prevent numerous diseases. Regular testing for vitamin D levels helps determine the appropriate dosage and adjust intake as needed. Vitamin D3 is pivotal, but the cumulative effects should not be overlooked!
Read More
